ClawCures

An autonomous AI agent that works until it finds a cure to every disease. Built on OpenClaw, it separates planning from execution and orchestrates full discovery campaigns end to end.

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Autonomous Campaign Loops
OpenClaw Planning Engine
Strict Tool Allowlist
JSON Reproducible Plans

What Is ClawCures?

ClawCures is a disease-campaign orchestration system that separates planning from execution. OpenClaw generates strategic plans through its /v1/responses endpoint, while refua-mcp executes typed scientific tools in a strict, auditable workflow.

By default, ClawCures pursues a singular, ambitious objective: find cures for all diseases by prioritizing the highest-burden conditions and researching the best drug design strategies for each.

Key Capabilities

  • Single-run planner/executor flow
  • Autonomous planner/critic loop with policy checks
  • Offline plan validation and dry-run modes
  • Portfolio ranking for disease-program prioritization
  • Strict JSON tool plans for full reproducibility

How It Works

Define Objective

Set a disease target or let ClawCures default to its all-disease mission.

Plan via OpenClaw

The planner generates a strict JSON tool-call plan through the OpenClaw gateway.

Validate & Review

Policy checks and optional human review ensure the plan meets safety and scientific constraints.

Execute with Refua MCP

Typed scientific tools run the actual folding, affinity predictions, and design workflows.

Critique & Iterate

In autonomous mode, a critic evaluates results and triggers additional rounds as needed.

CLI Commands

▶️

ClawCures run

Execute a single planner + execution cycle. Supports custom objectives, plan files, dry-run mode, and output artifact paths.

🔄

ClawCures run-autonomous

Multi-round planner/critic loop that autonomously iterates until the campaign objective is satisfied or limits are reached.

✅

ClawCures validate-plan

Policy-check a local JSON plan offline without making any API calls or running scientific tools.

📊

ClawCures rank-portfolio

Rank disease programs from a JSON input file to prioritize the most impactful targets.

Get Started

Installation

pip install ClawCures

Run the Default All-Disease Mission

ClawCures run

Or do a dry-run first:

ClawCures run --dry-run

Cure Every Disease

ClawCures is the autonomous engine behind the AgentCures mission. Start a campaign, review the plan, and let AI drive discovery forward.

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